Convalescent Plasma to Treat Hospitalized COVID-19 Patients

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They compared the number of units of plasma distributed to U.S. hospitals from blood banks on a per patient basis to the number of reported COVID-19 deaths per hospital admission across the country.


After analysing two datasets the researchers generated a model that suggests the COVID-19 case fatality rate decreased by 1.8 percentage points for every 10-percentage point increase in the rate of plasma use but other factors like changes in the average age of hospitalized patients, and the emergence of new variants of the COVID-19-causing coronavirus also influence the mortality rate.

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Even the clinical trials with negative results used plasma mainly as an antiviral treatment did not explore its effect late in the course of COVID-19.

So, this study urges physicians, policymakers, and regulator to consider the totality of the available evidence including this study findings for making decisions about convalescent plasma use in individual COVID-19 patients.

Source: Medindia

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