Global T-cell Lymphoma Pipeline Insight | Clinical Trials Evaluation Research Report 2022 by DelveInsight

Las Vegas, USA, May 31, 2022 (GLOBE NEWSWIRE) — Global T-cell Lymphoma Pipeline Insight | Clinical Trials Evaluation Research Report 2022 by DelveInsight

T-cell Lymphoma Pipeline constitutes 100+ key companies including Solasia Pharma, Genor Biopharma, ImmuneOncia Therapeutics, Hoffmann-La Roche, Soligenix, and several others are continuously working towards developing 100+ T-cell Lymphoma treatment therapies, analyzes DelveInsight. 

DelveInsight’s ‘T-cell Lymphoma Pipeline Insight 2022‘ report provides comprehensive global coverage of available, marketed, and pipeline T-cell Lymphoma therapies in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the T-cell Lymphoma pipeline domain.

Key Takeaways from the T-cell Lymphoma Pipeline Report

• DelveInsight’s T-cell Lymphoma Pipeline report depicts a robust space with 100+ active players working to develop 100+ pipeline therapies for T-cell Lymphoma treatment. 
• The leading T-cell Lymphoma companies with various T-cell Lymphoma drugs include Jazz Pharmaceuticals, Genor Biopharma, Solasia Pharma, Celgene, Celleron Therapeutics, Seagen, Nanjing Sanhome Pharmaceutical, Merck Sharp & Dohme, Medevir, Bristol Myers Squibb, Pfizer, Innate Pharma, Dizal Pharmaceutical, Hoffman-La-Roche, Affirmed, ImmuneOncia Therapeutics, CerRx, Shandong New Time Pharmaceutical, Secura Bio, Janssen Biotech, CStone Pharmaceutical, Galderma, Bioniz, Portola Pharmaceuticals, VidacPharma, Shanghai Yingli Pharmaceutical, ViGenCell, Daiichi Sankyo, Chia Tai Tianqing Pharmaceutical Group, BeiGene, Kura Oncology, Rafael Pharmaceuticals, Eutilex, Yake Biotechnology, Rhizen Pharmaceuticals, Eli Lilly and Company, Onyx Pharmaceuticals, Astex Therapeutics, Aileron Therapeutics, Autolus, Akeso Biopharma, AVM Biotechnology, Ayala Pharmaceuticals, C4 Therapeutics, Legend Biotech, Corvus Pharmaceuticals, Soligenix, Inc., Innovent Biologics, Citius Pharmaceuticals, Dialectic Therapeutics, and others are developing novel drug candidates to improve the T-cell Lymphoma treatment landscape.
• Key T-cell Lymphoma pipeline therapies in various stages of development include JZP-458, Geptanolimab, SP-02, CC-486, Zabinostat, Brentuximab Vedotin, SHC014748M, Pembrolizumab, SHP-141, Nivolumab, Lorlatinib, Lacutamab, AZD-4205, Atezolizumab, AFM13, IMC-001, Fenretinide, F 520, Duvelisib, Daratumumab, CS1001, CD 11301, BNZ 1, Cerdulatinib, VDA-1102, Lenalidomide, YY-20394, VT-EBV-N, Valemetostat, TQ-B3525, BGB-A317, Tipifarnib, Devimistat, EBViNT, RP 6530, LY3039478, Durvalumab, ASTX660, Carfilzomib, ALRN-6924, AUTO4, AK104, AVM-0703, and others.
• In May 2022, Myeloid Therapeutics dosed the first patient in the Phase I/II IMAGINE trial of MT-101 in patients with r/r peripheral T cell lymphoma (PTCL). MT-101 is the first mRNA engineered CAR monocyte-derived from the company’s ATAK platform. MT-101 targets CD5.
• AUTO4 is a programmed T cell product candidate in clinical development for T cell lymphoma, a setting where there are currently no approved programmed T cell therapies. AUTO4 is specifically designed to target TRBC1-derived cancers, which account for approximately 40% of T cell lymphomas, and is a complement to the AUTO5 T cell product candidate, which is in pre-clinical development. In May 2022, Autolus reported that it continues to enroll patients into the AUTO4 Phase I clinical trial, which is progressing through its dose-escalation phase. Interim Phase I data will be presented as an oral presentation at the EHA Congress in June. 
• In May 2022, EQRx, Inc. reported financial results and reported that an oral presentation featuring the primary analysis from the Phase II GEMSTONE-201 study of sugemalimab in relapsed or refractory Extranodal NK/T cell lymphoma (ENKTL) will be given at the 2022 ASCO Annual Meeting. The Phase II GEMSTONE-201 trial met its primary endpoint of objective response rate (ORR) in patients with relapsed or refractory ENKTL.
• In May 2022, Soligenix announced that it anticipates to submit a new drug application (NDA) to the US Food and Drug Administration (FDA) for marketing authorization of HyBryte (SGX301 or synthetic hypericin) in the treatment of cutaneous T-cell lymphoma (CTCL) in the second half of this year.
• In April 2022, US FDA has granted fast track designation to DT2216 for adult patients with relapsed or refractory peripheral T-cell lymphoma (PTCL) and cutaneous T-cell lymphoma (CTCL). DT2216 is Dialectic’s first-generation compound built using its proprietary and novel Antiapoptotic Protein Targeted Degradation (APTaD™) technology platform.
• In April 2022, Citius Pharmaceuticals reported topline results from the pivotal Phase III trial of I/ONTAK (E7777), an engineered IL-2-diphtheria toxin fusion protein, for the treatment of patients with persistent or recurrent cutaneous T-cell lymphoma (CTCL). The topline results for I/ONTAK (denileukin diftitox), a purified and more bioactive formulation of previously marketed ONTAK®, were consistent with the prior formulation. Moreover, no new safety signals were identified. Based on this data, Citius anticipates filing a biologics license application (BLA) with the US FDA in the second half of 2022.
• In February 2022, Dizal Pharmaceutical announced that the US FDA has granted Fast Track Designation to DZD4205 (Golidocitinib) for the treatment of patients with Refractory or Relapsed Peripheral T-Cell Lymphoma (r/r PTCL).
• In October 2021, Solasia Pharma and Nippon Kayaku announced the conclusion of a license agreement for marketing rights to darinaparsin (generic name, development code: SP-02) in Japan (hereinafter “this agreement”).

Request a sample and discover the recent developments in the T-cell Lymphoma pipeline @ T-cell Lymphoma Pipeline Outlook

The T-cell Lymphoma pipeline report provides detailed profiles of pipeline assets, a comparative analysis of clinical and non-clinical stage T-cell Lymphoma products, inactive and dormant assets, a comprehensive assessment of driving and restraining factors, and an assessment of opportunities and risks in the T-cell Lymphoma pipeline landscape.

T-cell Lymphoma Overview

T-cell Lymphomas (TCL) are a very heterogeneous group of lymphoid malignancies formed from mature T cells that varies in terms of location, pathological characteristics, and clinical presentation. T-Cell Lymphomas can arise in lymphoid tissues such as the lymph nodes and spleen and outside of lymphoid tissues (i.e., gastrointestinal tract, liver, nasal cavity, skin, and others). TCL accounts for roughly 12% of all non-Hodgkin Lymphomas (NHLs) and is classified as cutaneous TCL (CTCL) or peripheral TCL (PTCL), which are further classified as nodal or extranodal (systemic). There are no definitive causes of T-cell Lymphoma subtypes.

T-cell Lymphoma symptoms vary widely based on the type of lymphoma. Some of the common T-cell Lymphoma symptoms are swollen lymph nodes, fever, night sweats, weight loss, fatigue, and others. The biopsy is the most commonly used test for T-cell Lymphoma diagnosis. The treatment for T-cell Lymphoma also depends on the type of lymphoma. Chemotherapy, CAR T-cell Therapy, stem cell transplants, targetted drug therapies, and others are mostly used as a treatment for T-cell Lymphoma.  

Find out more about treatment for T-cell Lymphoma@ CAR T-cell Therapy for Lymphoma 

A snapshot of the T-cell Lymphoma Pipeline Drugs mentioned in the report:

Learn more about the novel and emerging T-cell Lymphoma pipeline therapies @ T-cell Lymphoma Clinical Trials

T-cell Lymphoma Therapeutics Assessment

The T-cell Lymphoma Pipeline report proffers an integral view of the T-cell Lymphomaemerging novel therapies segmented by Stage, Product Type, Molecule Type, Mechanism of Action, and Route of Administration.

Scope of the T-cell Lymphoma Pipeline Report 

• Coverage: Global 
• Therapeutic Assessment By Product Type: Mono, Combination, Mono/Combination
• Therapeutic Assessment By Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Therapeutics Assessment By Route of Administration: Oral, Parenteral, Topical, Intravenous
• Therapeutics Assessment By Molecule Type: Bispecific antibody, CAR-T cell therapies, Gene therapies, Cell therapies, Monoclonal antibodies, Peptides, Recombinant proteins, Small molecule
• Therapeutics Assessment By Mechanism of Action: Apoptosis stimulants, Cell cycle inhibitors, Reactive oxygen species stimulants, Antimetabolites, DNA methylation inhibitors, Antibody-dependent cell cytotoxicity, Programmed cell death-1 ligand-1 inhibitors, T lymphocyte stimulants, Phagocyte stimulants, Cytotoxic T lymphocyte stimulants, Emt protein-tyrosine kinase inhibitors
• Key T-cell Lymphoma Companies: Jazz Pharmaceuticals, Genor Biopharma, Solasia Pharma, Celgene, Celleron Therapeutics, Seagen, Nanjing Sanhome Pharmaceutical, Merck Sharp & Dohme, Medevir, Bristol Myers Squibb, Pfizer, Innate Pharma, Dizal Pharmaceutical, Hoffman-La-Roche, Affirmed, ImmuneOncia Therapeutics, CerRx, Shandong New Time Pharmaceutical, Secura Bio, Janssen Biotech, CStone Pharmaceutical, Galderma, Bioniz, Portola Pharmaceuticals, VidacPharma, Shanghai Yingli Pharmaceutical, ViGenCell, Daiichi Sankyo, Chia Tai Tianqing Pharmaceutical Group, BeiGene, Kura Oncology, Rafael Pharmaceuticals, Eutilex, Yake Biotechnology, Rhizen Pharmaceuticals, Eli Lilly and Company, Onyx Pharmaceuticals, Astex Therapeutics, Aileron Therapeutics, Autolus, Akeso Biopharma, AVM Biotechnology, Ayala Pharmaceuticals, C4 Therapeutics, Legend Biotech, Corvus Pharmaceuticals, Soligenix, Inc., Innovent Biologics, Citius Pharmaceuticals, Dialectic Therapeutics, and others
• Key T-cell Lymphoma Pipeline Therapies: JZP-458, Geptanolimab, SP-02, CC-486, Zabinostat, Brentuximab Vedotin, SHC014748M, Pembrolizumab, SHP-141, Nivolumab, Lorlatinib, Lacutamab, AZD-4205, Atezolizumab, AFM13, IMC-001, Fenretinide, F 520, Duvelisib, Daratumumab, CS1001, CD 11301, BNZ 1, Cerdulatinib, VDA-1102, Lenalidomide, YY-20394, VT-EBV-N, Valemetostat, TQ-B3525, BGB-A317, Tipifarnib, Devimistat, EBViNT, RP 6530, LY3039478, Durvalumab, ASTX660, Carfilzomib, ALRN-6924, AUTO4, AK104, AVM-0703, and others.

Dive deep into rich insights into new T-cell Lymphoma drugs, visit @ Treatment for T-cell Lymphoma

Table of Contents

For further information on the T-cell Lymphoma pipeline therapeutics, reach out @ T-cell Lymphoma Drugs

Related Reports

T-cell Lymphoma Epidemiology

T-cell Lymphoma – Epidemiology Forecast–2032 report delivers an in-depth understanding of the T-cell Lymphoma, historical and forecasted epidemiology as well as the T-cell Lymphoma epidemiology trends.

CAR T-cell Therapy for Non-Hodgkin’s Lymphoma Pipeline

CAR T-cell Therapy for Non-Hodgkin’s Lymphoma Pipeline Insight, 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key CAR T-cell Therapy for Non-Hodgkin’s Lymphoma companies such as Juno Therapeutics, Caribou Biosciences, Allogene Therapeutics, among others.

CAR T-cell Therapy for Non-Hodgkin’s Lymphoma Market

CAR T-cell Therapy for Non-Hodgkin’s Lymphoma Market Insights, Epidemiology, and Market Forecast-2032 report delivers an in-depth understanding of the CAR T-cell Therapy for Non-Hodgkin’s Lymphoma, historical and forecasted epidemiology, market share of the individual therapies, and key companies involved like Juno Therapeutics, Caribou Biosciences, Allogene Therapeutics, and many more.

Natural Killer T-cell Lymphoma Pipeline

Natural Killer T-cell Lymphoma Pipeline Insight, 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key Natural Killer T-cell Lymphoma companies such as CStone Pharmaceuticals, Innovent Biologics, Otsuka Pharmaceutical, among others.

Peripheral T-cell Lymphomas Pipeline

Peripheral T-cell Lymphomas Pipeline Insight, 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key Peripheral T-cell Lymphomas companies such as Acrotech Biopharma LLC, HUYA Bioscience International, Seattle Genetics, Inc., among others.

Cutaneous T-cell Lymphoma Pipeline

Cutaneous T-cell Lymphoma Pipeline Insight, 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key Cutaneous T-cell Lymphoma companies such as Soligenix, Merck Sharp & Dohme Corp, Elorac, among others.
Other Trending Reports

Gender Dysphoria Market
Germany Healthcare Outlook
Biopsy Pipeline
Bacterial Conjunctivitis Market
Pediatric Growth Hormone Deficiency (PGHD) Market
Non Cystic Fibrosis Bronchiectasis Market
X-linked Retinitis Pigmentosa Market
Otitis Media Market
Central Retinal Vein Occlusion Market

Related Healthcare Blogs

Cutaneous T-cell Lymphoma Market
CAR T-cell Therapy Market

About DelveInsight

DelveInsight is a leading Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.  Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.

Connect With Us at LinkedIn | Facebook | Twitter