Notice: amp_is_available was called incorrectly. `amp_is_available()` (or `amp_is_request()`, formerly `is_amp_endpoint()`) was called too early and so it will not work properly. WordPress is currently doing the `pre_get_posts` hook. Calling this function before the `wp` action means it will not have access to `WP_Query` and the queried object to determine if it is an AMP response, thus neither the `amp_skip_post()` filter nor the AMP enabled toggle will be considered. It appears the theme with slug `publisher` is responsible; please contact the author. Please see Debugging in WordPress for more information. (This message was added in version 2.0.0.) in /home/runcloud/webapps/techilive/wp-includes/functions.php on line 5313
Low blood flow in the brain may be an early sign of Parkinson's disease - TechiLive.in

Low blood flow in the brain may be an early sign of Parkinson’s disease

0

Patients who suffer from REM sleep behaviour disorder have altered blood flow in the brain, which can lead to a lack of oxygen in the brain tissue. In the long term, this may cause symptoms of Parkinson’s disease. This is shown by research from Aarhus University and Aarhus University Hospital.

Do you sleep restlessly and flail your arms and kick out in your sleep? This could be a sign of a disorder associated with diseases of the brain. Researchers from AU and AUH have examined whether the sleep disorder RBD — which is also known as Rapid Eye Movement Sleep Behaviour Disorder — may be an early sign of Parkinson’s disease.

“We can see complications in the small blood vessels of the brain in patients with RBD, although these patients don’t otherwise have any symptoms and the brain doesn’t show other signs of disease,” says Simon Fristed Eskildsen, who is behind the study.

Loading...

He explains:

“We believe that the same disease processes that cause disrupted sleep also affect the ability to control the blood flow in the brain, which can lead to a lack of oxygen in the brain tissue. Over time this will gradually break down the brain tissue and cause symptoms that we see in Parkinson’s disease.”

Monitored while asleep

Loading...

The changes in the brain are associated with reduced neurotransmitters, meaning that nerves in the brain have trouble controlling the blood vessels.

Loading...

“A medical treatment would be able to restore the neurotransmitter and control of the blood vessels, thereby helping to maintain the cognitive function of patients who show early signs of Parkinson’s disease,” explains the researcher.

Twenty RBD patients aged 54-77 years and 25 healthy control subjects aged 58-76 participated in the study. The participants in the study were monitored in a sleep laboratory, where they had their EEG (electrical activity in the brain), EOG (eye movements), EMG (muscle activity) and ECG (electrical activity in the heart) measured during sleep.

“The patients and the control subjects were tested cognitively and MRI scanned, and the results revealed low blood flow and flow disturbances in the small blood vessels in the brain in the patients compared with the control group. In the patients, these flow disturbances seen in the cerebral cortex were associated with language comprehension, visual construction and recognition — this was also associated with reduced cognitive performance,” says last author of the study, Nicola Pavese.

Loading...

The researchers will now investigate whether the reduced blood flow in the brain deteriorates over time and how it is linked to the symptoms of Parkinson’s disease. The hope is that it will be possible to use the method to predict the disease in patients with sleep disorders in order to then prevent the symptoms at an early stage.

The results have just been published in the scientific journal Brain.

Parkinson’s disease

Loading...

There are 7300 patients with Parkinson’s disease in Denmark. Symptoms are slow movements, often with shaking, together with muscular rigidity. Parkinson’s disease is a chronic condition that continues to worsen over time. About half of the patients experience cognitive decline early in the disease. The disease is somewhat more common in men than in women. Parkinson’s disease occurs because the brain lacks dopamine. It primarily affects adults and the first signs most often appear between the ages of 50-70.

Story Source:

Materials provided by Aarhus University. Original written by Helle Horskjær Hansen. Note: Content may be edited for style and length.

Loading...

Stay connected with us on social media platform for instant update click here to join our  Twitter, & Facebook

We are now on Telegram. Click here to join our channel (@TechiUpdate) and stay updated with the latest Technology headlines.

For all the latest Health News Click Here 

Loading...

 For the latest news and updates, follow us on Google News

Read original article here

Denial of responsibility! TechiLive.in is an automatic aggregator around the global media. All the content are available free on Internet. We have just arranged it in one platform for educational purpose only. In each content, the hyperlink to the primary source is specified. All trademarks belong to their rightful owners, all materials to their authors. If you are the owner of the content and do not want us to publish your materials on our website, please contact us by email – admin@techilive.in. The content will be deleted within 24 hours.

Loading...
Leave a comment